Cmpd # Ki (nM) cLogP HAC LE Mol
2 0.008 5.684 31 0.358
18 0.029 3.443 27 0.39
17 0.038 3.143 28 0.372
4 0.047 3.967 27 0.383
14 0.054 2.717 28 0.367
15 0.061 3.017 27 0.378
12 0.11 3.979 29 0.343
10 0.12 3.553 29 0.342
9 0.13 3.553 29 0.341
Pyp-1 0.23 2.652 28 0.344
16 0.33 3.135 26 0.365
3 0.44 3.362 27 0.347
7 0.49 4.158 29 0.321
13 0.6 2.708 26 0.355
11 0.87 3.553 29 0.312
5 3.2 3.967 27 0.315
6 7.8 3.313 26 0.312
8 8.6 3.553 29 0.278
1 8700.0 2.969 12 0.422