Cmpd # | Ki (nM) | cLogP | HAC | LE | Mol |
---|---|---|---|---|---|
2 | 0.008 | 5.684 | 31 | 0.358 | |
18 | 0.029 | 3.443 | 27 | 0.39 | |
17 | 0.038 | 3.143 | 28 | 0.372 | |
4 | 0.047 | 3.967 | 27 | 0.383 | |
14 | 0.054 | 2.717 | 28 | 0.367 | |
15 | 0.061 | 3.017 | 27 | 0.378 | |
12 | 0.11 | 3.979 | 29 | 0.343 | |
10 | 0.12 | 3.553 | 29 | 0.342 | |
9 | 0.13 | 3.553 | 29 | 0.341 | |
Pyp-1 | 0.23 | 2.652 | 28 | 0.344 | |
16 | 0.33 | 3.135 | 26 | 0.365 | |
3 | 0.44 | 3.362 | 27 | 0.347 | |
7 | 0.49 | 4.158 | 29 | 0.321 | |
13 | 0.6 | 2.708 | 26 | 0.355 | |
11 | 0.87 | 3.553 | 29 | 0.312 | |
5 | 3.2 | 3.967 | 27 | 0.315 | |
6 | 7.8 | 3.313 | 26 | 0.312 | |
8 | 8.6 | 3.553 | 29 | 0.278 | |
1 | 8700.0 | 2.969 | 12 | 0.422 |